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Blog posts tagged with 'AdVnt biotechnologies'

Sinking Teeth Into The Mysteries of Plague

Two plague victims in Aschheim-Bajuwarenring cemetery in Bavaria, Germany who died some 1500 years ago have been unearthed and are able to help provide an international team of scientists with a better understanding the type of virus that was responsible for their deaths sometime between 541 and 543. Thanks to the dental remains of these two unearthed plague victims, researchers using very sophisticated methods were able to extract DNA fragments of plague from the teeth from the skeletal remains and reconstruct the genome of what is now the oldest pathogen obtained to date. Yersinia Pestis or Y. Pestis is also known as plague. This bacterium was found to be responsible for the Justinian outbreak and the results showed that this was unique and distinct from various other strains that would later become the Black Death and other plague pandemics that would follow.

“This study raises intriguing questions about why a pathogen that was both so successful and so deadly suddenly died out. One testable possibility is that human populations evolved to become less susceptible,” says Edward Holmes, an NHMRC Australia Fellow at the University of Sydney.

Up until now little has been known about the exact cause of the Justinian epidemic’s origins or cause. The Justinian plague is thought to have been instrumental in bringing about the end of the Roman Empire and was, until the recent findings were too discover, responsible for the Black Death. The Justinian Plague is believed to have killed 30 to 50 million people, estimated to have been at least half of the world’s population at that time. Later the Black Death would emerge to ravage the medieval population killing 50 million Europeans between 1347 and 1351 some 800 years later. These recent findings now show that the Justinian plague was a unrelated strain from the plague that caused the Black Death.

The new results that are published in online edition of The Lancet Infectious Disease, show that the Justinian Plague was a distinct and separate genome of the same Pathogen know as Yersinia Pestis and not an evolutionary forefather or related to the same Yersinia Pestis strains responsible for the Black Death. Another pandemic that had taken hold in Hong Kong and spread across the globe is now more likely to be considered the precursor to the Black Death.

These findings would suggest that the Justinian pandemic strain also originated in Asia and not in Africa as some scientist originally thought. This would lead them to theorize that earlier epidemics, such as the Plague of Athens (430 BC) and the Antoine Plague (165 – 180 AD) may have also been unique and distinct emergence of related Yersinia Pestis strains.

“We know the bacterium Y. Pestis has jumped from rodents into humans throughout history and rodent reservoirs of plague still exist today in many parts of the world. If the Justinian plague could erupt in the human population, cause a massive pandemic, and then die out, it suggest it could happen again. Fortunately we now have antibiotics that could be used to effectively treat plague, which lessens the chances of another large scale human pandemic” says Dave Wagner, an associate professor in the Center for Microbial Genetics and Genomics at Northern Arizona University.

These studies would suggest that the threat of an outbreak of Yersinia Pestis can occur at any time now, or in the future, is quite possible. Add to this, the possibility of some individual or person intent to using the pathogen as a weapon to wreck terror on an unsuspecting population raises the stakes even higher. New technologies are now available to health and safety teams in the early detection of such possible natural outbreaks and first responders now have the capabilities to be able to equip themselves with the latest tools required to easily and reliably detect not only Yersinia Pestis, but other possible pathogens that could be used as weapons against humanity. This ability to provide early detection is essential in containing and maintaining control of a terrorist planned outbreak and is crucial to preventing another full scale global population pandemic such as those seen in the past.

One of the biggest breakthroughs in rapid and reliable early detection of pathogens that can be utilized against terrorist is the BADD line of bio-warfare detection tests produced by AdVnt Biotechnologies LLC. Developed in response to the white powder incidents that occurred after 9/11, the tests were used in the detection of bio-warfare pathogens during the Iraq War. This line of tests gave first responders the ability to arrive at a possible bio-threat scene and test for powders and liquids left by suspected terrorist and ascertain within 15-minutes or less if the material held the potential of becoming a cause of wide spread contamination. This rapid testing with their on-the-scene detection capabilities helped to open windows of opportunities for immediate containment and control of a possible pandemic. AdVnt Biotechnologies was also the first to revolutionize the hand held assays when they were the first to develop a testing platform that allows for the collection of one suspicious sample of unknown origin to be tested against multiple targets on one detection test cassette. In the not too distant past, responders would have to collect up to 5 samples and run 5 tests one at a time to discover what active agent provided the danger of contamination. If there was very little or sparse material left behind, the residue would have to be sent off site to be examined while the clock was ticking. With the invention of AdVnt Biotechnologies ground breaking PS-5T Pro-Strip multi-agent rapid screening system, for the first time, responders have the ability to hit five different targets from one collected bio-threat sample. Saving time, saving resources, saving lives.

AdVntures in Mycotoxicology - A Beginners Guide

Informant 15-Minute Black Mold Detection Test

Being able to understand the differences in determining what constitutes the definition of Fungus, Mold, Mildew, Algae or even something basic as Slime can be a bit confusing. Some of these differences can be determined by taking a few moments to ‘look under the hood’ and see what these species are composed of and why they are given their own unique identification. You will want to pay close attention to the following lesson since there will be a test… Just kidding.

When it comes to understanding differences in a species it is always best to understand how to define them in order to know what sets each of them apart. In the case of Fungus, Mold, Mildew, and Algae this is of the utmost importance since the relationship of each is almost closely associated with the other either through mis-identification or by sharing true similarities.

Let us begin with gaining a understanding of Fungus, what exactly is it and how is it defined. Fungus or its’ plural Fungi is defined as any diverse group of eukaryotic single-celled or multi-nucleate organisms that live by decomposing and absorbing the organic material in which they grow. Think of the ‘Pods’ from ‘Invasion of the Body Snatchers’. OK, maybe not to that extreme but it does hint at one of Fungi’s more pervasive attributes of proliferation which we will cover shortly. Fungus is comprised of several genii of different species such as Mushroom, Molds, Mildew, Smuts, Rusts, and Yeasts. Fungus itself is considered to be of the kingdom Plantae. As we learned in our high school science class that eukaryotic means …“any organism having as its fundamental structural unit a cell type that contains a specialized organelles in the cytoplasm, a membrane-bound nucleus enclosing genetic material organized into chromosomes and an elaborate system of division by mitosis or meiosis, characteristic of all life forms except bacteria and blue-green algae and other primitive micro-organisms” so I know I won’t need to spend time explaining the definition so we can tackle more of the interesting concepts that lay before us. To refresh your memory of what you learned in your science lab, mitosis is the usual method of cell division and meiosis is the process of gamete formation, consisting of chromosome conjugation and a two cell division. After all, gamete formation is something we live with every day and should all be used to by now. As you have already learned, Mold and Mildew have been mentioned as being a part of the Fungi family and Fungus as a whole is not only a family but a royal one belonging to a kingdom. Now that’s impressive.

Now let’s move on to gaining a deeper understanding of Algae. I can sense your excitement about this and I totally understand. Algae is something of a horse of a different color and is defined as “any numerous groups of chlorophyll containing mainly aquatic eukaryotic organisms ranging from microscopic single-celled forms to multi-cellular forms that are able to grow 100 feet or more, this growth is distinguished from plants by the absence of having roots, stems, and leaves as they are defined and by a lack of nonproductive cells in the reproductive structures: Classified into six phyla Euglenophyta, Crysophyta, Pyrrophyta, Chlorophyta , Phaeophyta and Rhodophyta.” Did you notice there is no kingdom for this horse? The singular pronouncement is Alga. Alga is a latin word meaning ‘Seaweed’ and this meaning is retained in its’ translation so if you know your latin, then this is something you already knew so go to the head of the class. Now the next time you are in a Chinese restaurant and they serve you up a bowl of seaweed soup, be sure to ask for a side of Alga. You will be the life of the party.

Now do I really need to define Slime? What would any meaningful discussion be without it? Slime is defined as that gelatinous goo that shows up in the best creature feature and “is composed of a thin, glutinous mud, or any ropy (that being stringy) or viscous liquid matter or a viscous secretion of animal or vegetable origin.” Let’s face it, what would a jaw retracting space alien be without slime?

So now it is understood that there is a big difference in Fungus and Algae and both mold and mildew are related in a fuzzy, smelly, unwanted growth kind of way. Not unlike reality TV, only more interesting and includes slime as one of the main characters, although now it’s seems, slime, which can be found on fungus and algae may be considered a byproduct and not its own species.

Alas we have opened the proverbial “hood” so it’s timefor us to continue to dig a little deeper into the the fungus side of things. Beginning with the infamous and ever present Mold, “a growth of minute fungi forming on vegetable or animal matter (aka, organic), and usually appears as a downy or furry coating, and requires decay or dampness. ” The proper English spelling is written as mould and we all know the English are funny that way. With Mildew the difference gets to be a little more fuzzy in more ways then one. Defined as “a disease of plants, characterized by a cottony, usually whitish coating on the surface of affected parts, caused by any of various fungi, aka mold, and can include any discolorations which appear on fabrics, paper, leather, ect. When…and this is most important…exposed to moisture. ” Emphasis added and you may now consider yourself enlightened. But wait, it gets even better!…again…just kidding.

Molds include all species of microscopic fungi that grow in the form of multi-cellular filaments called hyphae. This is unlike another fungi that grow as a single cell which are commonly called yeast. The hypae form a connected network of tubular branches, it has DNA and is considered a single organism referred to as a colony or in more technical terms a mycelium. Molds do not form a specific taxonomic or phylogenetic grouping, but can be found in the divisions Zygomycota, Deureromycota and Ascomycota. I often tell people I am phylogenetic just to see the worried look on their faces. Then I cough and watch the fun unravel.

Although some molds can cause disease, three species have been singled out by the CDC to have this evil superpower. Now there are other types of Fungus that can cause health issues as well, but for now we will concentrate on the Mold part of the kingdom. Some molds can cause food spoilage and others are actually useful in bio-degrading or in producing edible food products, beverages, antibiotic, and enzymes. There are thousands of known varieties of mold and their primary energy source is organic matter which is broken down by enzymes released from the mycelia (you know, the hyphae) into simple compounds decomposing organic matter enabling decay and rot necessary in all eco systems (that’s were the bio-degradable properties kick in). The enzymes and ‘mycotoxins’ that are a byproduct of this breakdown process can also prevent or compete with other molds and micro-organisms making them competitive for territory and will keep other mold types or plants from growing. In the case of Black Mold, it is these ‘mycotoxins’ that can cause harm to human health. Molds do not require or need sunlight to receive energy, another thing that distinguishes this from other plant species.

Now for a word of warning for the more sensitive reader’s, the next portion of this lesson discusses the reproductive characteristics of our topic and we will be getting all up in to the private lives of mold so it is permissible for those who are sensitive to close your eyes during this portion of our study.

Mold reproduces asexually through small spores, which can remain airborne indefinitely. Spores are hardy little buggers and can survive in the most extreme environments. Some mold can even grow at temperature lows such as 2 degrees Celsius. When conditions do not promote mold growth, (even though an environment that is only 2 degrees Celsius does not seem to very promotional for growth), molds can remain alive but in a dormant state for a very long time in the harshest conditions. This is how mold growth can suddenly appear inside building structures long after the building was completed. Moving air is not conducive to mold growth since this tends to cause a lower humidity. Remember, moisture is key here. Since mold must grow on organic matter, their presence is only visible to the naked eye where conditions have allowed colonies to grow and proliferate. Molds come in a variety of colors but gray, green, white and black are the most common and it is important to note that color does not define any one species. Black Mold does not necessarily have to be black to be Black Mold, a common mistake.

If you should toxic have mold ever present in your home then try to get rid of it right away. It is vital that you clean the affected area and throw away any contaminated materials. If there are large areas in your home that are affected, it is recommended you consider a mold remediation service as soon as possible because the longer it grows the more damage it can cause and the more money it will devour. Since mold can be a serious health issue it is also a good idea to know if the growth in your house is toxic or more specifically, ‘mycotoxic’.

It is for this reason AdVnt Biotechnologies LLC, has developed a way to test mold growth with a simple do it yourself test that can be done in the privacy of your home and will reveal if the type of mold growth infesting your home can bring harm to yourself and your family. The INFORMANT 15-Minute Black Mold Detection Test can show results in as little as 3 to 15 minutes after introducing the collected mold sample to the test. Remember, for mold to reach toxic levels it has to come to a stage in its growth cycle that will allow it to release mycotoxin’s through the process of decay as it eats at whatever organic material it is consuming. In homes this can be anything from the papers located on the drywall, wood frames used to fortify walls, carpet, clothing, leather goods, discarded debris in a basement, the list is endless. AdVnt’s ‘INFORMANT 15-Minute Black Mold Detection Test was created using the same advanced bio-technologies being deployed by first responders around the world to detect bio-warfare agents such as Anthrax, Ricin, Botulinum and Plague. Using the same science of applying active antibodies and antigens as genetic markers, AdVnt’s patented technology is designed to react specifically to the target species of black mold as mentioned earlier to be hazardous to human health as determined by the CDC. AdVnt’s INFORMANT 15-Minute Black Mold Detection Test can detect the most minute samples of Stachybotrys, Penicillium and its close cousin Aspergillius.

There is one last subject that we should tackle before dismissing class. Aflatoxin. This toxin is any various related mycotoxins produced by Aspergillus and is suspected of causing liver cancer in humans and other animals. That is the same Aspergillus that can be detected with the INFORMANT 15-Minute Black Mold Detection Test.

The INFORMANT is sold only online from AdVnt Biotechnologie’s website at www.advnt.org. The advantage to using our INFORMANT 15-Minute Black Mold Detection Test means you will know that if your tests show positive for either of these three species that the results will be conclusive and reliable. Since the INFORMANT Uses antigens and antibodies to detect black mold on a genetic level there will be no cross reaction with any other types of mold species or proteins. As an added bonus, each test purchased comes with everything required to run two complete tests.

Return of the Black Death

It may sound like a campy title to a old Hammer Film Horror Movie but unfortunately it’s real and it’s more common then you may think.

According to a article posted by Reuters on July 25, a Squirrel was found at the Angeles National Forest in California that was infected with the Plague. This has been the sixth squirrel located in Southern California’s San Gabriel Mountains since 1995 to test positive for the disease.

Authorities have shut down the park for at least a week while they have a chance to dust the burrows for fleas, which carry the bacteria and test more squirrels in the area. The most recent squirrel was trapped on July 16 during a routine check in the park and was confirmed to be carrying the disease on July 23.

Called the “Black Death” in history books due to the disease ravaging the European continent during the Middle Ages. Yersina Pestis (aka Y. Pestis) also known as Plague was responsible for killing more the 25 million people.

There on on average 7 cases a year that are reported in the United States and if discovered within a timely manner can be treated with antibiotics. According to the Center Disease for Control, almost all cases have been found in the Western United States and fortunately at this time none of these cases have been fatal.

Y. Pestis, Anthrax, Botulinum, Staphylococcal enterotoxin B (SEB) and Tularemia along with Ricin Toxin among others are currently under the Dept. of Homeland Security radar since they are all good candidates for being developed into a weapon that can be used by terrorist. As a result several protocols have been put into place to rapidly detect and deter such a horrific act form happening and putting plans in to play to dramatically minimize the event should one occur.

AdVnt Biotechnologies has been helping First Responders throughout the globe by offering a reliable, rapid and portable solution to the early detection of a bio-terror event with our line of BADD Single Agent Detection Test and Pro-Strip Rapid Screening System. Thanks to advancements in the area of Immunoassay Bio-Technology, Safety Professionals responding to a Bio-Terror threat event will have the tools they need to rapidly and accurately detect if the suspected agent involved is real emergency or a badly planned hoax, allowing them to put into place all the necessary safeguards that will be needed in order to contain and control such an event.

 

Hurricane recovery and the added dangers of black mold

In the short time that Hurricane Sandy flooded out many of the homes along the east coast. Sandy survivors were confronted with a multitude of serious issues such as low temperatures, damage to their homes and many other obstacles that is making recovery efforts a major uphill battle. One major issue many of them are being forced to contend with is rapid mold growth in their homes.

The health department states that they are closely monitoring emergency room visits and the hospitalization of those who are suffering respiratory illnesses as a key to determine if the threat of mold infestation is serious enough to warrant aggressive recovery action but is willing to admit there are no set guidelines to follow in the case of evacuating a region hard hit by mold infestation.

It’s important to understand mold reproduction starts when mature mold growth releases spores into the atmosphere. These spores are suspended in the air and are a part of the natural are we breathe on a daily basis and are the common cause of many of the allergies. Local weather stations will often include a mold count on their daily broadcast. The higher the number, the more likely there will be allergy sufferers.

Removing mold spores from any structure is almost impossible to control since the air outside will always find a way to get inside. Air conditioning filters and air purifiers can dramatically reduce the mold count in the environment; however it is almost impossible to completely be mold free.

The big problems with mold inside a building begin with water. Any area inside a structure that is always damp or has standing water is a prime setting for mold spores to collect and proliferate. Once mold spores locate a water source they will settle in and begin to grow. Mold growth can be very rapid in prime conditions therefore it is important at this stage to remove the mold infestation and dry out the infected area and most importantly, remove or bring under control the source of water that allowed the mold to grow. Without removing the source of water, mold will most certainly return.

Since last year, there are about 75,000 scientifically identifiable species of mold with a projection that there may be as many as 1 million fungal species that have yet to be identified. Not all mold species are harmful. Some are even beneficial such as those varieties that produce truffles and the various types that produce edible mushrooms. There is even a species of mold that has been proven capable of devouring toxic petroleum products and leaving behind a completely safe, environmentally friendly growth in its place. It use is currently being considered as a go to answer for cleaning oil spills. Some companies are even looking at mold to produce products such as toilet paper. Go figure.

Identification of a mold species is mostly dependent on costly DNA testing. AdVnt Biotechnologies as developed a black mold test that uses the genetic identifiers of black mold species to help identify toxic black mold from most common mold infestations. The INFORMANT 15-minute black mold test uses licensed antibodies to positively tag black mold spores for positive identification, therefore making sure that it does not show a positive result for more common mold varieties.

Toxic black mold is a species of mold, that if allowed to proliferate can produce a toxic substance known as mycotoxin. It is this substance derived from black mold growth that has been shown to be fatal to humans, especially those who suffer with compromised immune systems. There are to date, 3 known species that are known to produce this toxicity and can become a serious health hazard if left unchecked. Stachybotrys, Aspergillius and its close cousin Penicillium are the three species known to produce mycotoxins. The second requirement for mold growth is oxygen. Where conditions for mold growth are ripe, mycotoxins are produced as the mold expands and spreads into colonies releasing the toxic byproduct into the air. It is import to understand that mycotoxins as a result of growth of black mold is viewed differently than those cases of mycotoxins exposure that causes harm through the ingestion of misidentified mushrooms. In the case of toxicity to humans through mold growth, the victim is often not aware of the hazard until it causes some harm.

AdVnt Biotechnologies INFORMANT 15-Minute black mold detection test was specifically designed to test mold growth found in homes for this highly dangerous species. Each test kit with the items required to run two complete tests. The easy to follow step by step instruction sheet allows users to quickly identify if the mold growth in their homes is of the toxic variety. Waiting days for lab results is now a thing of the past. The INFORMANT 15-Minute black mold detection test can be purchased from our website at www.advnt.org. The INFORMANT Black Mold Detection Test is not available in stores.

The serious issues of black mold growth in the regions hit by hurricane Sandy are not ones to be taken with a grain of salt. Identifying and removing mold infestations are often tied in with a homeowners struggle to obtain the necessary funding in order to properly eradicate the infestation. The longer it takes for relief funding the more serious the situation can become. Complicated paperwork to get federal relief and slow moving insurers and politicians on the take is just a few of the many hurdles the victims of this tragic event will have to face in order to win back their homes and their peace of mind.

FBI Investigates Newest Anthrax Inhalation Exposure Case in US.

Government health officials have investigated a case of anthrax exposure after tests confirmed that a hospitalized individual had been infected with the dangerous bacteria; due to the deadly nature of anthrax and its feared use as a biological weapon back in 2001-02, the FBI joined Minnesota health officials in the investigation.

At least fourteen people died in 2002 in the last instances of undeniable anthrax terrorism in the USA.

Officials have concluded that the hospitalized individual became infected naturally after encountering the “non-weaponized” bacteria during his travels. The individual had travelled through several western states before becoming admitted for treatment in Minnesota.

An epidemiologist with the state, concluded that “Evidence points to this case of anthrax being caused by exposure to naturally occurring anthrax in the environment.”

What kind of a generalized, non-descriptive statement is this? Yes, it seems re-assuring in some sense, however, if the hearer had any understanding of how difficult this in fact is to occur, that being inhalation infection, you would be scratching your head, as we are.

I suppose this statement is made in hopes of assuring us that this was not a successful domestic terrorist attack utilizing highly concentrated weaponized anthrax. In such an instance there would be a large amount of suspicious white powder and some broadcast by a radicalized group taking responsibility for the terror evoking event.

In this instance, the individual had been exposed to soil and animal remains where the anthrax bacteria can easily be grown. The bacteria is known to develop in hooved animal carcasses each year in certain areas around the world.

The FBI determined that there was no evidence to suggest that the individual was infected as part of a criminal or terrorist act and the agency is no longer actively investigating the incident.

Health officials were careful to note that the public need not worry about potential anthrax exposure as these cases are extremely rare, unless you come in contact with the infectious source.

Health officials stressed that the case does not represent an increased risk of anthrax for the public. “Anthrax is not spread from person to person, and it is extremely rare for humans to become sickened with anthrax, especially through inhalation,” an official reported.

Only in rare cases do individuals become infected with anthrax by handling infected animal carcasses or ingest contaminated soil or meat from infected animals. People can also become infected by handling contaminated wool or hides from infected animals.

If this un-suspecting victim would have known about the world’s most effective hand-held anthrax detection device, AdVnt Biotechnologies’ “BADD” Anthrax environmental detection screening device, they would have known in less than fifteen (15) minutes that they were exposed to an infectious dose of the deadly bacteria. They could have saved their own life!

So consider, for your own personal safety and security, if you are going to be placed in harm’s way maybe being prepared and ready to screen for this deadly bacteria or a deadly toxin, like Botulinum or Ricin the technology exists today for less than $300. USD.

For a clear and concise understanding of the significance of this one event, I would draw attention to an article of some importance. “Pathogenic Ecology: Where have all the pathogens gone? Anthrax: A Classic Case.”

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New Study Shows Proof How Mold Targets Asthma Sufferers

According to an article in Indoor Environment Connections, vol. 11, issue 10 dated August 2010, a new scientific study shows a greater link between black mold and asthma. The study, which was conducted by Harvard researchers, says “There is a more definitive link then previously thought between mold in homes and the risk of severe asthma”. The study, which was originally published in the American Journal of Respiratory and Critical Care examined homes that contained high amounts of black mold and found children living in these environments, had “severe exacerbations of asthma that often included emergency room visits and hospitalization…” When studies such as these use words like “exacerbations” you can be sure the findings are not going to be good. The EPA places in-home mold threats on the same level as second hand smoke. The new study out of Harvard is now able to show that there is a more precise connection to mold and asthma then had been previously known. It is precisely for this reason that researchers at AdVnt Biotechnologies have worked to develop an in-home black mold detection test called ‘The Informant”. Inexpensive and easy to use, this remarkable test can determine the presence of black mold in 15-minutes or less with out the hassle of sending the results to a lab for further analysis. With this information, occupants of suspected mold infested homes will be armed with positive proof that action in mold remediation needs to be taken to prevent future long-term damage to their health and well-being.

Ann Wu of Harvard Medical School and Harvard Pilgrim Health Care Institute in Boston who conducted this new mold study explains that enzymes called chitinases that breakdown chitin found in cell walls of mold, causes asthma inflammation. “Our results support increasing evidence that CHIT1, which is primarily released in the lung, plays an important role in the patho-physiology of asthma in the proper environmental context of exposure to chitin, which was approximated by mold levels.” say Wu.

Homes that were used for this study were measured as having greater or less then 25,000 mold colonies per gram of household dust. Though this level is high for most homes, buildings that have problems with dampness, or water saturation in construction materials could have levels that easily reach these numbers. Often times homes that had sustained water damage in the past but had failed to completely remove all damaged materials, such as drywall, carpeting, vinyl floor coverings or wood could give rise to colonies that go undetected years before health problems occur. Click on the following link to see an article and video about one families horrific ordeal near Denver Colorado. http://www.9news.com/seenon9news/article.aspx?storyid=156994&catid=509. Testing for black mold in these environments becomes crucial and could mean the difference between better living or constant high cost visits to a hospital or emergency room. The ‘Informant 15-Minute Black-Mold Detection Test is highly accurate and can detect below 105 or 100,000 spores per ml of three of the most dangerous species of black mold listed by the Center for Disease Control.

As a result of this new study, people who have been pushing for tougher laws and regulations control and clean up of unsafe indoor environments now have documented, scientific evidence to back them up. One citizen, also in Denver CO. decided not to wait for the law to come a knocking chose to do the right thing. His heroic story can be found here… http://www.denverpost.com/entertainment/ci_16281174.

Low-income neighborhoods are at a greater risk for mold problems and asthma is a huge public health concern in these disadvantaged areas that are the hardest hit. Since many buildings at these locations are usually older and have long-standing repair issues in terms of wear and drainage damage, the probability of long-standing plumbing and moisture problems is much greater. Add to that the easily controlled, but seldom dealt with issues of slumlords who are able to slip through the cracks of a legal system that is often to overwhelm to adequately pursue such matters until the problem of black mold demands that they take action, the issues challenging low-income neighborhoods increase. Now with the help of the ‘Informant’ 15-Minute Black Mold Detection Test, occupants have a simple and easy to use instrument ready to help them make their case and take the steps that will be needed to reclaim their homes. See the article in the Phoenx Business Journal on AdVnt’s new “Infomant 15-Minute Black Mold Detection Test.

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Press Release - Informant 15-Minute Black Mold Detection Kit

Press Release

Phoenix, Arizona

FOR IMMEDIATE RELEASE:

Contact: ADVNT BIOTECHNOLOGIES,LLC
Contact Person: KEVIN BORAH
Company Name: ADVNT BIOTECHNOLOGIES, LLC
Fax Number (623) 879 – 9697
Email Address: http://www.advnt.org/contact/
Web site address:
www.advnt.org

Headline: Arizona Biotech Company Develops a Rapid Test Making The Detection Of Black Mold Simple- In 15 Minutes or Less.

Phoenix, AZ — JUNE 25th, 2010 — AdVnt Biotechnologies, the company that is known for producing BioWarfare Agent Detection Devices for HAZMAT First Response Teams around the globe to help them rapidly detect such biological agents as Anthrax, Ricin and Botulinum fhas just released it’s newest product for In-Home and Professional use. Building on the expertise gained in the international arena o BioWarfare Agent Detection, AdVnt is now applying its’ R&D expertise to help defend against another type of bio threat that could be growing in the walls and under the floorboards in your own home. BLACK MOLD! Now available for the first time from their website at www.advnt.org, AdVnts’ exciting new INFORMANT 15 MINUTE BLACK MOLD DETECTION TEST is now ready to be the first response in helping home owners combat the growing problem of Black Mold with a simple-to-use hand held test that can give results in 15 minutes or less.

The “Informant” is not a culture, settlement plate, a swab collection kit, or an ATP test. The “Informant” is a highly accurate testing technology called immunochromatographic assay, also known as a rapid test or Hand-Held Assay (HHA). Unlike the ATP test, which detects all living cells regardless of what those cells are, the “Informant 15 Minute Black Mold Detection Test” detects only specific sub-species of Aspergillus, Penicillium, and Stachybotrys. These types of black mold are the sub-species that have been determined to be hazardous to human health and welfare.

Mold in the home, of the “black” variety is a slimy dark greenish-black substance. It is most common in damp, moist areas of walls, ceilings and floors. Look for leaky pipes, leaky roofs, damp basements and crawl spaces, high humidity of over 55%, recent flooding, mildew and musty odors, allergy problems, condensation and/or rusting, wall discoloration, growth in grout and around bathroom floors. These are just a few of the signs that black mold may be present. Unfortunately, you cannot identify these species simply by sight. But with Advents’ new Informant 15 Minute Black Mold Detection Test” you can now identify toxic black mold quickly. Environmental testing for black mold in homes and business is critical, as it can be a serious threat to your health.

Last, but not least, the speed and accuracy of the “Informant 15 Minute Black Mold Detection Test” will make it is a desirable tool for the professional in the industry. Its’ very fast, specific and accurate performance is due to the very special patented monoclonal antibodies that AdVnt uses to create each test. This makes the test ideal for use in construction, remediation, real estate and insurance industries. So whether you are a home owner wanting to insure the health and safety of your family, or a working professional who knows the importance of having an early, rapid detection capability to help with making crucial decisions when confronted with black mold issues, the Informant is ready to be put to the test.

If you are interested in giving the Informant 15-minute Black Mold Detection Test a try, visit AdVnt Biotechnologies’ website at www.advnt.org and click on buy now under the Informant label.

For more information please visit Advnts’ website at http://www.advnt.org or

Contact http://www.advnt.org/contact/

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It Creeps, It Crawls, it climbs on walls...

For movie fans, this line may bring back memories of a popular 1950′s science fiction movie starring the late great actor Steve McQueen called “The Blob”. In this creature feature a grey slimy glob of space goo from outer space falls to earth with a voracious appetite and proceeds to eat on the denizens of small town USA. As the creature consumes its unwilling victims it takes on the form of a big red glob of goo, hence the making of the creative title. This cosmic space sludge would slowly and methodically ooze its way through floorboards, sink drains, walls and air vents allowing it to sneak up on its unsuspecting victims, cover them up and ingest them. What’s interesting about ‘The Blob’ is that it uses the same exact modes of home invasion as does toxic Black Mold. Areas in homes that have been damp for long periods of time are susceptible to Black Mold spores taking root and settling in and spreading throughout a household as quietly and efficiently has ‘The Blob’. And since it is not a big red glob with molecular stability issues but microscopic airborne spores that can be everywhere and not even be seen, the idea of Black Mold could even be considered more threatening. This concept was not lost on Hollywood either, other such fungi infested features sprung to life in those no to distant days of Hollywood, The classic British yarn “Day of the Triffids” featured cannibalistic space plants that grew out of a space based fungus and the popular “Invasion of the Body Snatchers” were also banking on the fear of the unseen flesh devouring microbes to bring home the box office shivers.

Most recently in the film “The Happening” a mysterious ‘Red Fungus’ comes out of nowhere to cause entire populations of individuals to suddenly have a desire to commit suicide. This of course wrecks havoc on the day-to-day activities of it’s bewildered cast and a ten-dollar hole in the wallets of the unlucky masses that filed in to see this drama play out on a big screen. Unlike the cosmic invaders of yester year, this time the threat is explained as a defense mechanism built into the earth’s eco-system to help maintain a natural balance to human over population, making it an even greater ‘Inconvenient Truth’.

Although we may never see a horror film from Hollywood featuring the horrifically nasty black crawling slime known as “BLACK MOLD” (music builds to crescendo), the amount of damage that this primordial black substance can bring to an unsuspecting household, or an unknowing bystander can be just as horrific. Sometimes reality can be stranger then fiction and the devastation that can come from simple environmental fungi is no exception. Aside from the harsh impact it can have on health and finances, Black Mold has been known to take out more buildings then a man in a rubber Godzilla suit. Millions of dollars are lost every year to buildings that have to be destroyed because no one realized until it was too late that Black Mold, hiding behind walls, growing under floorboards and crawling through vents, had been growing undetected in the dark places. Now, thanks to Hollywood, we all know about those dark places, and it knows what scares you.

Then there’s the innocent victims who sit quietly at home watching a large fish consume unsuspecting beach goers in “Human Sushi II” while microscopic mold spores are unknowingly inhaled into their lungs and up their nostrils causing their immune systems to go to defcon 5. Then after several days, they find themselves short of breath, congested, sore throat, nausea, and suffering from memory loss or screen writer’s block. Many of them will make costly medical visits and consume large amounts of over the counter medications that will at best temporarily alleviate the symptoms but never really cure anything. But then a select few may discover the cause of their woes and respond, but countless others will be trapped in a vicious cycle of ongoing health conditions and over medicated futures.

Then, suddenly, ‘in a world’ where all seems lost, one hero takes the stage, armed with a small plastic device; he single handedly takes on the unseen perpetrator and exposes it for what it is. AdVnt Biotechnologies’ new INFORMANT Black Mold Detection Test as the power to turn innocent victims into well informed problem solvers. With one simple device that can expose the villainous Black Mold Spores in the privacy and comfort of one’s own home, you can now take back control of your health, and save your home from uncertain destruction and save the day with a simple and easy to use tool designed to give rapid results within the time it takes to turn off a cell phone. The INFORMANT is a Hand Held Assay, not unlike a pregnancy test, specifically test positive for the presence of the three types of Black Mold spores and their subspecies that are known by the CDC to create health issues. Stachybotrys, Aspergillus, and Penicillium. Using patented antibodies, each test can show reactivity within 15 minutes or less and can be stored for up to 2 years. AdVnt Biotechnology is one of the leading manufactures of Hand Held Assays used by Home Land Security and First Response Teams worldwide. Rapid Biowarfare Detection is what they do. For years they have helped save countless lives from the biowarfare agents such as Anthrax, Ricin, and Botulinum released by terrorist on unsuspecting civilians in devious plots more sinister then anything dreamed up on a soundstage. Now they have applied their expertise to a different kind of threat on the home front with their new INFORMANT 15 Minute Black Mold Detection Test. Now we won’t need another hero.

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ANCIENT BIOTHREATS part II

It is the year 184 BC and you are a soldier on a Pergamene Ship headed to Carthage to confront the opposing forces of that mega barbarion superstar known as Hannibal. As you near your destination and prepare to put all the years of your razor sharp warfare training and barbarian bashing expertise to the test, your are focused on how you are going to show this tyrant what a real warrior is all about. When suddenly, and without warning, something in the corner of your eye blocks out the sun for just a tic and catches your attention. then CRASH.

A large object clay pot shatters on the deck of your ship. Your first reaction is to grab some water or a blanket fearing the enemy has attacked your vessel with a pot of burning oil and coal, but instead of flames and smoke spreading on the deck of the ship, you are shocked to discover that lying among broken shards of clay fragments are hundreds of poisonous snakes of various varieties slithering and swarming all over the deck in all directions. Cobra’s sliding under the feet of those beloved slaves chained to the oars. Large Black Mamba’s wrapping themselves around post, and disrupting the captain’s afternoon tea. These fanged vermin are angry and not feeling very loved. Why should they? After being packed in a cramped pot like moldy roman grain and tossed through the air like the heads of Roman disidents at a gladiator free for all, these snakes have a serious attitude problem. Fast and vicious, within seconds they have already have bitten more then half the crew. The few remaining stoic warriors have decided to take their chances in the shark infested ocean waters and bravely abandon ship.

Before you can join in this decision to run away, you find yourself surrounded by a swarm of fanged attitude and the only thing you know to do besides scream like a captured carpathian in hot boiling oil is to start beating these misplaced reptilians with your trusty sword. But these snakes are fast and three of them have already gotten a few bites in on your sandal-clad ankles while several others are squirming closer. As the poision starts to set in, confusion and frustration starts to slowly give way to a sinking feeling swimming around in your head as neurotoxin courses through your veins and nausea and pain begin to register shades of Elysian Fields. Your last thoughts is the realization of why you hate snakes. Let there be no doubt about it, Biowarfare is a nasty business and not for the mortally challenged.

With the passage of time comes change, instead of clay pots, biowarfare can come in the form of a dirty bomb, a discarded package, a letter sent by the mailman, the happy fellow you have known since high school or a misplaced clay pot full of scorpions sitting unnoticed on the promenade deck of a large luxury liner. Strange has it may seem, some things never change. Although most modern bioterrorist find bravery in not confronting their enemies face to face, it is safe to say they too are afraid of snakes. Though proven to be a formidable weapon, snakes have now slithered aside and have been replaced by prayer books and lab coats. Clay shards now look like powders or toxic gasses and instead of a few hundred crewmembers on a long wooden war vessel; the victims are now in shopping malls, school yards and sports arenas can now number in the tens of thousands. Let there be not doubt about it, these are not the good times.

Now lets take a look at that sword and the improvements that can only come with the blessings of time. Back in the day, the sword would have held back a few of the vermin, but even the craftiest war trained soldier would have found himself at a great disadvantage. Now the snakes are powders and liquids and a simple 2-inch by 3-inch plastic hand held device and an easy to use plastic buffer bottle that can test suspicious bio threat residuals with given results in less then ten minutes. With that type of knowledge in hand, first responders will be able to make valued decisions that can save the lives of millions, making it better then a sword and much easier to carry.

Though not designed to ward off a pot full and angry vipers, AdVnt Biotechnologies newly extended line of Bio Warfare detection devices are both time and field tested to support bio threat first responders with rapid need to know information that many of us rather not know. Detecting threats for Anthrax, Ricin, SEB, Botulinum, Plaque or Tularemia, AdVnt’s BADD single test and Pro-Strip Rapid Screening System are the tools to have when confronted with a real-time biowarfare situation. And with the addition of the new Tularemia test device, the blanket of threat detection as spread even wider.

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The Long Lasting Legacy of Biowarfare

What was once known as ‘Germ Warfare’ for decades is now being termed ‘Biowarfare or Bioterrorism in keeping with the current state of affairs. Unfortunately biowarfare is not a new tactic in warfare, in fact biowarefare’s roots go way back to the ancient history of dirty warfare tactics. One example of ancient biowarfare assults can be found in the fourteenth century when Asian armies catapulted the bodies of plague victims over city walls to infect the entrapped population of a fortified city. Later, during the French and Indian Wars in the United States, a British Military officer is reported to have given unsuspecting Indians blankets infected with small pox resulting in several fatalities. The US militia are said to have continued this same tactic on the American Indians as the US expanded further into the western territories.
In Modern times, in Sverdlovsk Russia, anthrax spores were released from a military facility some 1450 km east of Moscow resulted in 100 deaths in 1979. That same year, Ricin another biological warfare toxin is said to be a preferred poison with the KGB, was used to coat the assassin’s bullet that killed Bulgarian dissident writer Georgi Markov on September 7, 1978. The use of anthrax spores as a weapon was implemented in WW II when both Japan and Great Britain tested weapons carrying anthrax spores.
The development in recent times of genetic engineering holds the grim and disturbing promise of manufactured toxins never before experienced on this planet. Genetically altering already harmful microorganisms into super harmful mutations is no longer the stuff of science fiction and comic book villains. Biological Warfare and all its’ ramifications as been with us throughout our history and promises to become more formidable as we move forward into the future.
In 2003 AdVnt biotechnologies sought to pave the way in responding to the growing threat of biowarfare by creating a rapid hand held assay that would give hazmat, and emergency first responder teams a way to identify a biowarfare agent in less then 15 minutes, giving these teams plenty of time to make important containment decisions and save the lives of millions. Thanks to this pioneering technology, a rapid, low-cost solution to biowarfare threats has been greatly diminished.
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