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Blog posts tagged with 'hand held assay'

Sinking Teeth Into The Mysteries of Plague

Two plague victims in Aschheim-Bajuwarenring cemetery in Bavaria, Germany who died some 1500 years ago have been unearthed and are able to help provide an international team of scientists with a better understanding the type of virus that was responsible for their deaths sometime between 541 and 543. Thanks to the dental remains of these two unearthed plague victims, researchers using very sophisticated methods were able to extract DNA fragments of plague from the teeth from the skeletal remains and reconstruct the genome of what is now the oldest pathogen obtained to date. Yersinia Pestis or Y. Pestis is also known as plague. This bacterium was found to be responsible for the Justinian outbreak and the results showed that this was unique and distinct from various other strains that would later become the Black Death and other plague pandemics that would follow.

“This study raises intriguing questions about why a pathogen that was both so successful and so deadly suddenly died out. One testable possibility is that human populations evolved to become less susceptible,” says Edward Holmes, an NHMRC Australia Fellow at the University of Sydney.

Up until now little has been known about the exact cause of the Justinian epidemic’s origins or cause. The Justinian plague is thought to have been instrumental in bringing about the end of the Roman Empire and was, until the recent findings were too discover, responsible for the Black Death. The Justinian Plague is believed to have killed 30 to 50 million people, estimated to have been at least half of the world’s population at that time. Later the Black Death would emerge to ravage the medieval population killing 50 million Europeans between 1347 and 1351 some 800 years later. These recent findings now show that the Justinian plague was a unrelated strain from the plague that caused the Black Death.

The new results that are published in online edition of The Lancet Infectious Disease, show that the Justinian Plague was a distinct and separate genome of the same Pathogen know as Yersinia Pestis and not an evolutionary forefather or related to the same Yersinia Pestis strains responsible for the Black Death. Another pandemic that had taken hold in Hong Kong and spread across the globe is now more likely to be considered the precursor to the Black Death.

These findings would suggest that the Justinian pandemic strain also originated in Asia and not in Africa as some scientist originally thought. This would lead them to theorize that earlier epidemics, such as the Plague of Athens (430 BC) and the Antoine Plague (165 – 180 AD) may have also been unique and distinct emergence of related Yersinia Pestis strains.

“We know the bacterium Y. Pestis has jumped from rodents into humans throughout history and rodent reservoirs of plague still exist today in many parts of the world. If the Justinian plague could erupt in the human population, cause a massive pandemic, and then die out, it suggest it could happen again. Fortunately we now have antibiotics that could be used to effectively treat plague, which lessens the chances of another large scale human pandemic” says Dave Wagner, an associate professor in the Center for Microbial Genetics and Genomics at Northern Arizona University.

These studies would suggest that the threat of an outbreak of Yersinia Pestis can occur at any time now, or in the future, is quite possible. Add to this, the possibility of some individual or person intent to using the pathogen as a weapon to wreck terror on an unsuspecting population raises the stakes even higher. New technologies are now available to health and safety teams in the early detection of such possible natural outbreaks and first responders now have the capabilities to be able to equip themselves with the latest tools required to easily and reliably detect not only Yersinia Pestis, but other possible pathogens that could be used as weapons against humanity. This ability to provide early detection is essential in containing and maintaining control of a terrorist planned outbreak and is crucial to preventing another full scale global population pandemic such as those seen in the past.

One of the biggest breakthroughs in rapid and reliable early detection of pathogens that can be utilized against terrorist is the BADD line of bio-warfare detection tests produced by AdVnt Biotechnologies LLC. Developed in response to the white powder incidents that occurred after 9/11, the tests were used in the detection of bio-warfare pathogens during the Iraq War. This line of tests gave first responders the ability to arrive at a possible bio-threat scene and test for powders and liquids left by suspected terrorist and ascertain within 15-minutes or less if the material held the potential of becoming a cause of wide spread contamination. This rapid testing with their on-the-scene detection capabilities helped to open windows of opportunities for immediate containment and control of a possible pandemic. AdVnt Biotechnologies was also the first to revolutionize the hand held assays when they were the first to develop a testing platform that allows for the collection of one suspicious sample of unknown origin to be tested against multiple targets on one detection test cassette. In the not too distant past, responders would have to collect up to 5 samples and run 5 tests one at a time to discover what active agent provided the danger of contamination. If there was very little or sparse material left behind, the residue would have to be sent off site to be examined while the clock was ticking. With the invention of AdVnt Biotechnologies ground breaking PS-5T Pro-Strip multi-agent rapid screening system, for the first time, responders have the ability to hit five different targets from one collected bio-threat sample. Saving time, saving resources, saving lives.

Press Release - Informant 15-Minute Black Mold Detection Kit

Press Release

Phoenix, Arizona

FOR IMMEDIATE RELEASE:

Contact: ADVNT BIOTECHNOLOGIES,LLC
Contact Person: KEVIN BORAH
Company Name: ADVNT BIOTECHNOLOGIES, LLC
Fax Number (623) 879 – 9697
Email Address: http://www.advnt.org/contact/
Web site address:
www.advnt.org

Headline: Arizona Biotech Company Develops a Rapid Test Making The Detection Of Black Mold Simple- In 15 Minutes or Less.

Phoenix, AZ — JUNE 25th, 2010 — AdVnt Biotechnologies, the company that is known for producing BioWarfare Agent Detection Devices for HAZMAT First Response Teams around the globe to help them rapidly detect such biological agents as Anthrax, Ricin and Botulinum fhas just released it’s newest product for In-Home and Professional use. Building on the expertise gained in the international arena o BioWarfare Agent Detection, AdVnt is now applying its’ R&D expertise to help defend against another type of bio threat that could be growing in the walls and under the floorboards in your own home. BLACK MOLD! Now available for the first time from their website at www.advnt.org, AdVnts’ exciting new INFORMANT 15 MINUTE BLACK MOLD DETECTION TEST is now ready to be the first response in helping home owners combat the growing problem of Black Mold with a simple-to-use hand held test that can give results in 15 minutes or less.

The “Informant” is not a culture, settlement plate, a swab collection kit, or an ATP test. The “Informant” is a highly accurate testing technology called immunochromatographic assay, also known as a rapid test or Hand-Held Assay (HHA). Unlike the ATP test, which detects all living cells regardless of what those cells are, the “Informant 15 Minute Black Mold Detection Test” detects only specific sub-species of Aspergillus, Penicillium, and Stachybotrys. These types of black mold are the sub-species that have been determined to be hazardous to human health and welfare.

Mold in the home, of the “black” variety is a slimy dark greenish-black substance. It is most common in damp, moist areas of walls, ceilings and floors. Look for leaky pipes, leaky roofs, damp basements and crawl spaces, high humidity of over 55%, recent flooding, mildew and musty odors, allergy problems, condensation and/or rusting, wall discoloration, growth in grout and around bathroom floors. These are just a few of the signs that black mold may be present. Unfortunately, you cannot identify these species simply by sight. But with Advents’ new Informant 15 Minute Black Mold Detection Test” you can now identify toxic black mold quickly. Environmental testing for black mold in homes and business is critical, as it can be a serious threat to your health.

Last, but not least, the speed and accuracy of the “Informant 15 Minute Black Mold Detection Test” will make it is a desirable tool for the professional in the industry. Its’ very fast, specific and accurate performance is due to the very special patented monoclonal antibodies that AdVnt uses to create each test. This makes the test ideal for use in construction, remediation, real estate and insurance industries. So whether you are a home owner wanting to insure the health and safety of your family, or a working professional who knows the importance of having an early, rapid detection capability to help with making crucial decisions when confronted with black mold issues, the Informant is ready to be put to the test.

If you are interested in giving the Informant 15-minute Black Mold Detection Test a try, visit AdVnt Biotechnologies’ website at www.advnt.org and click on buy now under the Informant label.

For more information please visit Advnts’ website at http://www.advnt.org or

Contact http://www.advnt.org/contact/

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It Creeps, It Crawls, it climbs on walls...

For movie fans, this line may bring back memories of a popular 1950′s science fiction movie starring the late great actor Steve McQueen called “The Blob”. In this creature feature a grey slimy glob of space goo from outer space falls to earth with a voracious appetite and proceeds to eat on the denizens of small town USA. As the creature consumes its unwilling victims it takes on the form of a big red glob of goo, hence the making of the creative title. This cosmic space sludge would slowly and methodically ooze its way through floorboards, sink drains, walls and air vents allowing it to sneak up on its unsuspecting victims, cover them up and ingest them. What’s interesting about ‘The Blob’ is that it uses the same exact modes of home invasion as does toxic Black Mold. Areas in homes that have been damp for long periods of time are susceptible to Black Mold spores taking root and settling in and spreading throughout a household as quietly and efficiently has ‘The Blob’. And since it is not a big red glob with molecular stability issues but microscopic airborne spores that can be everywhere and not even be seen, the idea of Black Mold could even be considered more threatening. This concept was not lost on Hollywood either, other such fungi infested features sprung to life in those no to distant days of Hollywood, The classic British yarn “Day of the Triffids” featured cannibalistic space plants that grew out of a space based fungus and the popular “Invasion of the Body Snatchers” were also banking on the fear of the unseen flesh devouring microbes to bring home the box office shivers.

Most recently in the film “The Happening” a mysterious ‘Red Fungus’ comes out of nowhere to cause entire populations of individuals to suddenly have a desire to commit suicide. This of course wrecks havoc on the day-to-day activities of it’s bewildered cast and a ten-dollar hole in the wallets of the unlucky masses that filed in to see this drama play out on a big screen. Unlike the cosmic invaders of yester year, this time the threat is explained as a defense mechanism built into the earth’s eco-system to help maintain a natural balance to human over population, making it an even greater ‘Inconvenient Truth’.

Although we may never see a horror film from Hollywood featuring the horrifically nasty black crawling slime known as “BLACK MOLD” (music builds to crescendo), the amount of damage that this primordial black substance can bring to an unsuspecting household, or an unknowing bystander can be just as horrific. Sometimes reality can be stranger then fiction and the devastation that can come from simple environmental fungi is no exception. Aside from the harsh impact it can have on health and finances, Black Mold has been known to take out more buildings then a man in a rubber Godzilla suit. Millions of dollars are lost every year to buildings that have to be destroyed because no one realized until it was too late that Black Mold, hiding behind walls, growing under floorboards and crawling through vents, had been growing undetected in the dark places. Now, thanks to Hollywood, we all know about those dark places, and it knows what scares you.

Then there’s the innocent victims who sit quietly at home watching a large fish consume unsuspecting beach goers in “Human Sushi II” while microscopic mold spores are unknowingly inhaled into their lungs and up their nostrils causing their immune systems to go to defcon 5. Then after several days, they find themselves short of breath, congested, sore throat, nausea, and suffering from memory loss or screen writer’s block. Many of them will make costly medical visits and consume large amounts of over the counter medications that will at best temporarily alleviate the symptoms but never really cure anything. But then a select few may discover the cause of their woes and respond, but countless others will be trapped in a vicious cycle of ongoing health conditions and over medicated futures.

Then, suddenly, ‘in a world’ where all seems lost, one hero takes the stage, armed with a small plastic device; he single handedly takes on the unseen perpetrator and exposes it for what it is. AdVnt Biotechnologies’ new INFORMANT Black Mold Detection Test as the power to turn innocent victims into well informed problem solvers. With one simple device that can expose the villainous Black Mold Spores in the privacy and comfort of one’s own home, you can now take back control of your health, and save your home from uncertain destruction and save the day with a simple and easy to use tool designed to give rapid results within the time it takes to turn off a cell phone. The INFORMANT is a Hand Held Assay, not unlike a pregnancy test, specifically test positive for the presence of the three types of Black Mold spores and their subspecies that are known by the CDC to create health issues. Stachybotrys, Aspergillus, and Penicillium. Using patented antibodies, each test can show reactivity within 15 minutes or less and can be stored for up to 2 years. AdVnt Biotechnology is one of the leading manufactures of Hand Held Assays used by Home Land Security and First Response Teams worldwide. Rapid Biowarfare Detection is what they do. For years they have helped save countless lives from the biowarfare agents such as Anthrax, Ricin, and Botulinum released by terrorist on unsuspecting civilians in devious plots more sinister then anything dreamed up on a soundstage. Now they have applied their expertise to a different kind of threat on the home front with their new INFORMANT 15 Minute Black Mold Detection Test. Now we won’t need another hero.

To opt in for AdVnt Biotechnologies product updates & notifications follow this link… http://eepurl.com/gYvBv

Black Mold adds insult to injury for flood victims

Flooding in the Country Music capital of the world has reached catastrophic proportions for many of the residence of Nashville Tennessee. As many homeowners try to restore their homes back to their former glory, many are finding themselves faced with another natural catastrophe literally growing beneath their floorboards, behind cabinets and in their drywalls. Taking advantage of the longstanding waters and wet materials that often remain for days during the clean-up and restoration process of flood remediation, Nashville residence find themselves deeply immersed in trying to prevent their homes from being overrun with the fast growing, disgusting presence of black mold. For months after a major flood, the lingering damp, humid conditions that hover over a flood plain provide the perfect Petri-dish like environment that mold thrives in and spreads at alarmingly exponential rates. The high cost of this infestation can easily run in the thousands of dollars for the average homeowner and upwards in the millions of dollars on the city and state levels. In Phoenix Arizona, one of the nations most dry and arid climates there are at least 20 listings for mold remediation crews alone.

Recently reported that in Antlers OK. US congressman Dan Boren announced that the Antlers Public school system would be receiving a large 3 million dollar portion of a federal grant to build a new elementary school to replace the severely water damaged and mold infested Brantley Elementary.

Soon homeowners and city officials will have a new tool on their side to help them in the early detection and remediation battle to offset the damages caused by black mold. Thanks to the creation of AdVnt’s soon to be released ‘In Home Mold Detection Kit’, the rapid and early detection and elimination can begin long before the spores have a chance to proliferate. Using a simple Hand Held Assay, and a small sample from a suspected area, a person can determine in 10 minutes or less weather or not immediate remediation action will need to be taken. No special unit will need to be called out to the house, no samples will need to be sent to the lab, the simple easy to follow instructions will allow for a quick private assessment of the situation before one phone call needs to made.

To opt in for AdVnt Biotechnologies product updates & notifications follow this link… http://eepurl.com/gYvBv